Seronegative Arthritis: Is It Treatable?


Seronegative Arthritis: Is It Treatable?

What is Seronegative Arthritis?

Seronegative  Arthritis or RA is a condition that causes swelling and pain in joints. It’s different from other kinds of arthritis. It’s a lifelong condition. RA causes inflammation swelling redness and pain and it can damage the joints.

Every person has an immune system to be able to fight infections such as bacteria or viruses. In RA the body’s immune system begins to attack its own joints and can sometimes attack other parts of the body.

Factors Causing Seronegative  Arthritis


  • Chronic infection
  • Scanning of the liver
  • Abnormal proteins in the blood
  • Inflammatory lung disease
  • Sjogren’s syndrome
  • Inflammatory muscle disease
  • Cancer
  • Lupus

No one knows exactly why RA can begin in any joint. It can eventually affect all of them wrists hands, knees, ankles, shoulders, leading to stiff swollen, or painful joints the lining inside of the joint is called synovium. In RA the synovium becomes inflamed and swollen causing pain and stiffness. There is no cure for RA but the drugs can slow down the disease.

If left untreated RA will get worse without treatment. The inflammation will continue to damage and eventually destroy the joints organs and other parts of the body.

The inflammation can affect other organs such as the eyes or lungs. Any organ can suffer. RA can even cause disability such as difficulty using your hands or problems standing and walking. RA is a serious condition.

It requires treatment and monitoring by a doctor to prevent additional problems. 

All these drugs medicines are the main treatment for RA. They relieve pain and reduce swelling and joints. Most people with RA need to keep taking their medicines for life.

Two kinds of RA medicines DMARDs and steroids are used. DMARDs stand for disease-modifying antirheumatic drugs. These medicines relieve inflammation and pain. They also slow or sometimes stop the changes in your joints.

There are many different DMARDs uggs. Some are in pill form some are injections or shots and others are given intravenously or IV through a needle.

In your vein, there are at least 10 different demons. They each have a generic name and one or more different brand names.

You can find a list of all of the current ones in your guide. One of the standard DMARDs that’s often used is called methotrexate.

Symptoms of Seronegative  Rheumatoid Arthritis

Some of the most important symptoms of Seronegative  Arthritis include:
  • Joint pain
  • Swelling
  • Redness
  • Joint tenderness
  • Fatigue
  • Eye redness
  • Morning stiffness
  • Inflammation
  • Symmetrical symptoms
  • Nodules under the skin
  • Loss of cartilage.

It’s a pill for many people, it works as well as other DMARDs that are given by shot or intravenously your IV. Most of the DMARDs that are given either as an injection or by IV are a newer class of drugs that are also sometimes called biologic demons because they have a different way of acting and standard DMARDs like methotrexate.

Sometimes doctors will prescribe an of medicines one or more standard DMARDs or a combination containing a standard and a biologic d Mart the other drugs we use are called steroids drugs.

Like prednisone, these are man-made forms of hormones made by your own adrenal glands. These drugs help with joint pain and swelling. There is some evidence that like DMARDs they may slow down the damage to your joints.

Your main treatment will be one or more of the DMARDs and steroids as recommended by your doctor.  Your doctor may also prescribe a non-steroidal anti-inflammatory drug.

An NSAID likes ibuprofen or naproxen help with the pain and inflammation of many patients with seronegative arthritis. It may take some time to find the best combination of medicines if one medicine or a combination of medicines.

How to control seronegative arthritis: 

How long do you need to take these medicines when I got my first symptoms of RA I started feeling like every joint in my body was sore.

 It was unable for me to even walk because of the pain it was almost impossible to walk downstairs most mornings and leaving my house for the day was a nightmare. 

 I took some pain pills but they didn’t help much and I felt like my body really started to swell up. My doc told me that I should see a Rheumatologist. One of those docs that specialized in joints and she prescribes the medication called methotrexate.

I was doing okay with the methotrexate. My doctor told me to take six pills that I took all at one time once a week. He also gave me some other pills called prednisone.

I took methotrexate for two years with no side effects after that I started to have liver problems. Then my doctor recommended an injection called anti TNF which is a biological therapy. I’m always scared to start taking a new drug especially when it’s a shot. So I was a little nervous about it especially because I needed to inject myself. 

Most people only need to have it once every few weeks DMARDs.

 Do not start working right away it may take weeks or months to start working. So you may need other medications like steroids or pain medicines. The steroids that are used are not the same ones you hear about athletes misusing. Remember that steroids may slow down the damage to your joints that is seen in x-ray and they may help to alleviate the symptoms.

They can have side effects if they’re used for a long time so your doctor will probably try to use them sparingly only when you need them all of these medicines can help you but they are powerful so you’ll need to be careful about certain things one of those things is infections.

 RA is caused by your immune system attacking your own tissues so all of the drugs we use are designed to suppress your immune system to make it less active but since your immune system also protects you by fighting infections drugs that suppress it can put you at higher risk of infection, in other words, it’ll be easier for you to get infections when you’re taking these medicines.

You’ll need to be more careful about staying away from people who have colds and flu because you will be more likely to catch what they have your doctor will probably want you to get flu shots but don’t get any other vaccines without asking your doctor you’ll also need to pay closer attention to wounds or sores things that might normally heal to make sure they don’t get infected.

Seronegative Arthritis

What you have to do:

If you do have a sore or wound that isn’t healing or you get an infection. Let your doctor know right away finally many of these medicines can cause birth defects. So both men and women who take them should use not just one but two forms of birth control a condom and a birth control pill. For example, to prevent a pregnancy this is something you and your partner should talk with the doctor.

RA medicines are powerful they also have the potential for unwanted side effects. Some of these can be serious be sure to read the drug information that the pharmacist gives. So be alert to any unwanted reactions and report them to your doctor.

Diagnostic with seronegative arthritis:

 I was diagnosed with RA six months ago at the ER after waking up with unbearable pain one morning I didn’t know what was wrong the ER doctor said I had seronegative arthritis and had most likely had it for a few years.

 I used to feel quite sore all over my joints wrists hands shoulders feet and sometimes my knees especially in the mornings and after working in my garden for a while I would take a painkiller and the pain would go away after a while but then it would come back the ER doctor said I needed to follow up with the rheumatologist to start a treatment plan.

 I finally got in to see a Rheumatologist she explained that seronegative arthritis is a disease that affects the joints it’s a lifelong disease and if it goes untreated it can cause lots of damage to the joints and can even cause deformation. The rheumatologist said there are different kinds of rheumatoid arthritis medications and each has its own benefits and risks.

DMARDs are one type of medication that helps to get rid of the pain but also helps slow down the disease she said we would try Adi Marg medication called methotrexate.

Take steroid for immediate relief:

It will take a while to work and she gave me a steroid to take with the methotrexate in the meantime the steroid is for more immediate relief she said that since I was having a lot of pain I should take the steroid daily and then once the methotrexate started working we could see about decreasing or even not needing to take the steroid.

It could continue the pain medication. I was given at the ER is needed well just after two months of taking methotrexate. I was able to get out of bed in the morning without much pain.

I even made breakfast for my family. It’s been six months and I have not needed the steroid for quite some time now I only take methotrexate.

Staying active and eating right no junk food as I said need to continue to follow up with Doctor regularly to make sure I’m not having any problems from the medications and my seronegative arthritis is under control to prevent any painful flare-ups. I have rheumatoid arthritis but since my doctor and I have been working together and keeping it under control I have felt absolutely terrific now that I feel better and in more control, I have also asked my doctor about other non-medication treatments that can be useful for rheumatoid arthritis.

Exercises reduce pain in seronegative arthritis:

 Exercise can help people with rheumatoid arthritis experience less pain and depression and can have less disabling effects.

It may be proposed that exercise therapy has useful execution on increasing purgative skills rather than reducing the energy of the disease.

In a vex program for patients with RA, the following characteristics should be thinking: whether the involvement of the concerted is local or systemic, level of the disease, age of the longanimous, and submission of the patient with the therapy. It was easier for them to do mundane tasks like procurement dressed and washed or handling a stunner and a fork and knife.

Thus, patients with active seronegative arthritis should especially avoid activities such as scansorial stairs or weight lifting. 

Participants in the study cars using light weights or strengthening equipment for 30 to 60 tittle, two to three times per week. It also reveals overbearing effects. It amended the attribute of life, and it also had a conclusive effect on the limitations of diurnal life. The markers, which are found in the kinship, are anti-cyclic citrullinated peptide (anti-CCP) antibodies or rheumatoid agents.

Therapeutic Exercise Muscle weakness

In patients with RA may appear for immobilization or subjugation in activities of daily quickening. A low-intensity isokinetic salute trial (by 50% of the limit intended contraction) was hearsay to be safe and energetic in patients with seronegative arthritis.


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